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Evidence summary (Updated 2022)
A large body of good quality randomised controlled data shows physical activity will have improve coronary blood flow through better vascular endothelial function(1–8), reduced atherosclerosis(9–11) and better collateral flow(12–14) and perfusion(15,16). Two studies did however reveal acute or strenuous resistance(1) or aerobic exercise training(1,2) to be a potential risk of activating pro-inflammatory pathway of platelet aggregation.
Quality of Evidence
Grade A – moderate quality
Strength of recommendation
Grade 1 – strong recommendation
Conclusion
Physical activity can be recommended to improve the coronary flood flow in most patients with ischaemic heart disease and should be undertaken unless there are compelling reasons NOT to do so.
References
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